Home/Compounds/Pharmaceutical Intermediate/(S)-1,3-Piperidinedicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester
C21H21NO4
351.4 g/mol
Pharmaceutical IntermediateWarning
(3S)-1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidine-3-carboxylic acid
CAS193693-68-4EC675-809-0
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
This compound is a protected piperidine carboxylic acid derivative used as a building block in solid-phase peptide synthesis. Its fluorenylmethoxycarbonyl (Fmoc) group enables temporary protection of the amine during chain assembly.
Peptide synthesis intermediateFmoc-protected amino acid analogResearch reagent for solid-phase peptide synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 193693-68-4
Related Compounds
SimilarStructure SimilarSimilarity 0.72
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Referencestereoisomer of
(R)-1-Fmoc-piperidine-3-carboxylic acid
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Referencesame scaffold
3-(Aminomethyl)-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester hydrochloride
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Referencesame scaffold
3-Cyano-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(3S)-1-(9H-fluoren-9-ylmethoxycarbonyl)piperidine-3-carboxylic acid
InChIKey
FINXGQXNIBNREL-AWEZNQCLSA-N
SMILES
C1C[C@@H](CN(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
Synonyms (12)
- FMOC-L-NIP-OH
- FMOC-PIC(3)-OH
- L-1-Fmoc-Nipecotic acid
- fmoc-(s)-nipecotic acid