C27H31Br2ClN4O2
638.8 g/mol
APIWarning
Lonafarnib
CAS193275-84-2EC679-527-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Lonafarnib is an oral farnesyltransferase inhibitor, specifically an EC 2. 5.
Antineoplastic agentEC 2.5.1.58 (protein farnesyltransferase) inhibitor
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 193275-84-2
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Safety Reference
Warning
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide
InChIKey
DHMTURDWPRKSOA-RUZDIDTESA-N
SMILES
C1CN(CCC1CC(=O)N2CCC(CC2)[C@@H]3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N
Synonyms (25)
- Lonafarnib (JAN/USAN/INN)
- 1o5m
- Lonafarnib
- Lonafarnib (SCH66336)
- Lonafarnib (Standard)
- Lonafarnib, >=98% (HPLC)
- Sarasar
- Sch 66336
- Zokinvy
- Zokinvy (TN)
- lonafarnibum