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Home/Compounds/Research Reagent/O-tert-butyl-L-serine
C7H15NO3
161.2 g/mol
Research ReagentWarning

(2S)-2-amino-3-(tert-butoxy)propanoic acid

CAS18822-58-7EC606-131-5
Category
Research Reagent
Compound Class
Amine
Primary Use
Research Compound

O-tert-butyl-L-serine is a protected serine derivative used as a building block in peptide synthesis. The tert-butyl group shields the hydroxyl side chain, enabling selective deprotection during solid-phase peptide assembly.

Research compound for peptide synthesisBuilding block in solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid

InChIKey

DDCPKNYKNWXULB-YFKPBYRVSA-N

SMILES

CC(C)(C)OC[C@@H](C(=O)O)N

Synonyms (17)
  • H-Ser(But)-OH
  • H-Ser(tBu)-OH
  • L-Ser(tBu)-OH
  • L-serine tert-butyl ether
  • O-t-BUTYL-L-SERINE
  • O-tert-Butyl-L-serine
  • Ser(tBu)-OH
  • Serine tert-butyl ether
  • o-tert-butylserine