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Home/Compounds/Research Reagent/N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide
C22H30FN3O7
467.5 g/mol
Research Reagent

Z-VAD-fmk

CAS187389-52-2
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound

Z-VAD-fmk is a research reagent used as a pan-caspase inhibitor. It is a fluoromethylketone derivative that contains an aromatic ring and multiple amide bonds, commonly employed in laboratory studies to investigate apoptosis.

inhibitor of caspase activity in apoptosis researchlaboratory reagent for cell death studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

2,4-Dichlorothieno[2,3-d]pyrimidine

CAS18740-39-1

research compound

ReferenceSame Category

1-(3-fluorophenyl)-2-((2-hydroxyethyl)amino)propan-1-ol

CAS1874218-36-6

research compound

ReferenceSame Category

2-(3-NITROPHENYL)ACETIC ACID

CAS1877-73-2

research compound

ReferenceSame Category

SCHEMBL6047666

CAS187794-49-6

research compound

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Identifiers
IUPAC Name

methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate

InChIKey

MIFGOLAMNLSLGH-QOKNQOGYSA-N

SMILES

C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1

Synonyms (29)
  • 5-Bromo-2 -deoxyuridine
  • Z-L-Val-L-Ala-L-Asp(OMe)-CH2F
  • Z-VAD(OMe)-FMK
  • Z-VAD-fmk
  • Z-Val-Ala-Asp(OCH3)-CH2F
  • Z-Val-Ala-Asp(OMe)-CH2F
  • Z-Val-Ala-Asp(OMe)-FMK
  • pan-caspase inhibitor

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