C22H24ClFN4O3
446.9 g/mol
APIDanger
Gefitinib
CAS184475-35-2EC643-034-7
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Gefitinib is a chemical compound used as an active pharmaceutical ingredient in pharmaceutical manufacturing. It is an aromatic, ring-containing molecule with moderate lipophilicity and hydrogen-bond donor and acceptor sites.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 184475-35-2
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Safety Reference
Danger
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
InChIKey
XGALLCVXEZPNRQ-UHFFFAOYSA-N
SMILES
COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
Synonyms (34)
- G-4408
- IRE
- Gefitinib (JP18/USAN/INN)
- Gefitinib for system suitability, EuropePharmacopoeia (EP)
- Gefitinib, EuropePharmacopoeia (EP)
- GEFITINIB [MART.]
- Gefitini; Iressa
- Gefitinib
- Gefitinib (GMP)
- Gefitinib (Standard)
- Gefitinib - Bio-X trade mark
- Gefitinib CRS
- Gefitinib, >=98% (HPLC)
- Gefitinib,ZD-1839,Iressa
- Iressa
- Iressa (AstraZeneca)
- Iressa (TN)
- Iressa(TM)
- Irressat
- gefitinib (zd1839)
- gefitinibum