C45H57NO14
835.9 g/mol
APIDanger
Jevtana
CAS183133-96-2
Category
API
Compound Class
Ester
Primary Use
Pharmaceutical Raw Material
Jevtana is the brand name for cabazitaxel, an active pharmaceutical ingredient used in drug manufacturing. It functions as a microtubule inhibitor and is investigated for antineoplastic activity.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 183133-96-2
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Safety Reference
Danger
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
InChIKey
BMQGVNUXMIRLCK-OAGWZNDDSA-N
SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
Synonyms (33)
- EX-A838
- Cabazitaxel (USAN/INN)
- AB01273971-01
- CABAZITAXEL [MART.]
- Cabazitaxel (Jevtana)
- Cabazitaxel (Standard)
- Cabazitaxel Injection
- Cabazitaxelum
- Jevanta
- Jevtana
- Jevtana (TN)
- Jevtana Kit
- RPR-116258A
- TXD 258
- Taxoid XRP6258
- Xrp6258
- cabazitaxel acetonate
- kabazitaxel