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Home/Compounds/API/Azd 0156
C26H31N5O3
461.6 g/mol
API

Azd 0156

CAS1821428-35-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Azd 0156 is an orally bioavailable, potent and selective inhibitor of ataxia telangiectasia mutated (ATM) kinase, a serine/threonine protein kinase involved in DNA damage response. It is based on an imidazo[4,5-c]quinolin-2-one core and is used in research as a laboratory reagent to study ATM-mediated signaling and DNA repair.

research compound for ATM kinase inhibition studieslaboratory reagent for DNA damage response research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 1821428-35-6

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Identifiers
IUPAC Name

8-[6-[3-(dimethylamino)propoxy]-3-pyridinyl]-3-methyl-1-(oxan-4-yl)imidazo[4,5-c]quinolin-2-one

InChIKey

AOTRIQLYUAFVSC-UHFFFAOYSA-N

SMILES

CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4CCOCC4)C5=CN=C(C=C5)OCCCN(C)C

Synonyms (12)
  • ATM Kinase Inhibitor AZD0156
  • AZD0156 (AZD-0156)
  • Azd 0156
  • US9428503, 1