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Home/Compounds/Research Reagent/Trimethylsilyldiazomethane
C4H10N2Si
114.22 g/mol
Research ReagentDanger

Trimethylsilyldiazomethane

CAS18107-18-1EC605-915-4
Category
Research Reagent
Compound Class
Organometallic
Primary Use
Research Compound

Trimethylsilyldiazomethane is a reagent commonly used in organic synthesis. It serves as a safer alternative to diazomethane for reactions such as the esterification of carboxylic acids and the derivatization of phenols.

Reagent for organic synthesisDerivatization of phenolsPreparation of methyl esters from carboxylic acids

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Flammable
Flammable
Toxic
Toxic
Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H225Highly flammable liquid and vapour
H315Causes skin irritation
H330Fatal if inhaled
H331Toxic if inhaled
H350May cause cancer
H370Causes damage to organs
H373May cause damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name

diazomethyl(trimethyl)silane

InChIKey

ONDSBJMLAHVLMI-UHFFFAOYSA-N

SMILES

C[Si](C)(C)C=[N+]=[N-]

Synonyms (16)
  • TMSD
  • TMS-Diazomethane
  • Trimethlsilyl diazomethane
  • Trimethylsilyldiazomethane
  • diazomethyltrimethyl silane
  • trimethylsilyidiazomethane
  • trimethylsilyldiazomethan
  • trimethysilyldiazomethane