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Home/Compounds/Pharmaceutical Intermediate/(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
C17H29BF3NO4
379.2 g/mol
Pharmaceutical Intermediate

(R)-BoroLeu-(+)-Pinanediol trifluoroacetate

CAS179324-87-9
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

(R)-BoroLeu-(+)-Pinanediol trifluoroacetate is a boronic ester derivative used as an impurity or intermediate in the manufacturing of the pharmaceutical compound bortezomib. It is a salt-like, multi-component material with a defined stereochemistry, and its structure includes an amine group and a heterocyclic ring.

impurity or intermediate for bortezomib synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

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Referencesame scaffold

2-Methylpropaneboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester

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pharmaceutical intermediate

Identifiers
IUPAC Name

(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butan-1-amine;2,2,2-trifluoroacetic acid

InChIKey

SRFQKJZNJYTMNI-CDVUYJLHSA-N

SMILES

B1(O[C@@H]2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)N.C(=O)(C(F)(F)F)O

Synonyms (20)
  • Bortezomib Impurity 38
  • Bortezomib Impurity 61