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Home/Compounds/Pharmaceutical Intermediate/Cbz-D-(-)-Phenylglycine
C16H15NO4
285.29 g/mol
Pharmaceutical IntermediateWarning

(R)-(((Phenylmethoxy)carbonyl)amino)phenylacetic acid

CAS17609-52-8EC241-582-8
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

N-Carbobenzoxy-D-phenylglycine (Cbz-D-Phg-OH) is a protected amino acid derivative used in peptide synthesis. Its structure features a benzyloxycarbonyl (Cbz) protecting group on the amino group, enabling selective incorporation of D-phenylglycine into peptide chains.

Peptide synthesis building blockProtected amino acid for solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H319Causes serious eye irritation
Identifiers
IUPAC Name

(2R)-2-phenyl-2-(phenylmethoxycarbonylamino)acetic acid

InChIKey

RLDJWBVOZVJJOS-CQSZACIVSA-N

SMILES

C1=CC=C(C=C1)COC(=O)N[C@H](C2=CC=CC=C2)C(=O)O

Synonyms (21)
  • Cbz-D-(-)-Phenylglycine
  • Cbz-D-Phg-OH
  • Z-D-2-phenylglycine
  • Z-D-Phg-OH
  • Z-D-Phg-OH, >=99.0% (HPLC)