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Home/Compounds/API/Avapritinib
C26H27FN10
498.6 g/mol
API

Avapritinib

CAS1703793-34-3
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Avapritinib is a kinase inhibitor used as an active pharmaceutical ingredient in the manufacturing of medications for certain types of systemic mastocytosis and gastrointestinal stromal tumors with specific mutations.

Pharmaceutical raw material for kinase inhibitor-based therapiesCompound used in the production of drugs targeting PDGFRA exon 18 mutation-positive GIST

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Mavacoxib

CAS170569-88-7

pharmaceutical raw material

ReferenceSame Category

CHEMBL29923

CAS170570-01-1

pharmaceutical raw material

ReferenceSame Category

Aprepitant

CAS170729-80-3

pharmaceutical raw material

ReferenceSame Category

Ipamorelin

CAS170851-70-4

pharmaceutical raw material

Customs Tariff Classification

The international HS code for Avapritinib (CAS 1703793-34-3) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine

InChIKey

DWYRIWUZIJHQKQ-SANMLTNESA-N

SMILES

C[C@](C1=CC=C(C=C1)F)(C2=CN=C(N=C2)N3CCN(CC3)C4=NC=NN5C4=CC(=C5)C6=CN(N=C6)C)N

Synonyms (24)
  • 9JI
  • BLU-285
  • C-366
  • X-720776
  • Avapritinib (USAN/INN)
  • Avapritinib
  • Avapritinib (BLU-285)
  • Avapritinib (Standard)
  • Ayvakit
  • Ayvakit (TN)
  • Ayvakyt
  • Ayvakyt (TN)
  • BLU-285 (Avapritinib)
  • US10807985, Compound 44
  • avapritinibum

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