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Home/Compounds/Pharmaceutical Intermediate/(1S,2S)-(+)-N-(4-Toluenesulfonyl)-1,2-diphenylethylenediamine
C21H22N2O2S
366.5 g/mol
Pharmaceutical IntermediateWarning

(1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine

CAS167316-27-0EC626-353-6
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

This compound is a chiral sulfonamide ligand, specifically the (S,S)-enantiomer of N-(2-amino-1,2-diphenylethyl)-4-methylbenzenesulfonamide. It is widely used as a chiral ligand in asymmetric catalysis, particularly in transfer hydrogenation reactions.

chiral ligand for asymmetric catalysisused in transfer hydrogenation reactions

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Methyl N-Boc-piperidine-2-carboxylate

CAS167423-93-0

pharmaceutical intermediate

ReferenceSame Category

4-Methoxypyridine-2-carbaldehyde

CAS16744-81-3

pharmaceutical intermediate

ReferenceSame Category

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide

CAS1675248-19-7

pharmaceutical intermediate

ReferenceSame Category

Gamma-Benzyl L-glutamate

CAS1676-73-9

pharmaceutical intermediate

Referencestereoisomer of

(1R,2R)-(-)-N-(4-Toluenesulfonyl)-1,2-diphenylethylenediamine

CAS144222-34-4

research compound

Referencesame scaffold

N-[(1S,2S)-2-amino-1,2-diphenylethyl]-2,3,4,5,6-pentafluorobenzenesulfonamide

CAS313342-24-4

research compound

Referencesame scaffold

N-[(1S,2S)-2-amino-1,2-diphenylethyl]-2,4,6-tri(propan-2-yl)benzenesulfonamide

CAS247923-41-7

research compound

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide

InChIKey

UOPFIWYXBIHPIP-SFTDATJTSA-N

SMILES

CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](C2=CC=CC=C2)[C@H](C3=CC=CC=C3)N

Synonyms (18)
  • (1S,2S)-TSDPEN
  • (IS,2S)-TsDPEN
  • (S,S)-TSDPEN

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