Home/Compounds/Pharmaceutical Intermediate/(1S,2S)-(+)-N-(4-Toluenesulfonyl)-1,2-diphenylethylenediamine
C21H22N2O2S
366.5 g/mol
Pharmaceutical IntermediateWarning
(1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine
CAS167316-27-0EC626-353-6
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
This compound is a chiral sulfonamide ligand, specifically the (S,S)-enantiomer of N-(2-amino-1,2-diphenylethyl)-4-methylbenzenesulfonamide. It is widely used as a chiral ligand in asymmetric catalysis, particularly in transfer hydrogenation reactions.
chiral ligand for asymmetric catalysisused in transfer hydrogenation reactions
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 167316-27-0
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Referencestereoisomer of
(1R,2R)-(-)-N-(4-Toluenesulfonyl)-1,2-diphenylethylenediamine
CAS144222-34-4
research compound
Referencesame scaffold
N-[(1S,2S)-2-amino-1,2-diphenylethyl]-2,3,4,5,6-pentafluorobenzenesulfonamide
CAS313342-24-4
research compound
Referencesame scaffold
N-[(1S,2S)-2-amino-1,2-diphenylethyl]-2,4,6-tri(propan-2-yl)benzenesulfonamide
CAS247923-41-7
research compound
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide
InChIKey
UOPFIWYXBIHPIP-SFTDATJTSA-N
SMILES
CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](C2=CC=CC=C2)[C@H](C3=CC=CC=C3)N
Synonyms (18)
- (1S,2S)-TSDPEN
- (IS,2S)-TsDPEN
- (S,S)-TSDPEN