C21H23Cl2NO6
456.3 g/mol
APIDanger
Clevidipine
CAS167221-71-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Clevidipine is a dihydropyridine calcium channel blocker used as an active pharmaceutical ingredient for the reduction of blood pressure when oral therapy is not feasible or not desirable. It is administered intravenously and has a short half-life of approximately one minute, allowing practitioners to titrate the dose to achieve desired blood pressure control.
blood pressure reduction in hospital settingsintravenous antihypertensive agent
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 167221-71-8
Related Compounds
SimilarStructure SimilarSimilarity 0.78
Felodipine
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pharmaceutical raw material
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Tropine benzylate hydrochloride
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Ornidazole
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pharmaceutical raw material
Referencesame scaffold
Dimethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS43067-01-2
pharmaceutical raw material
Referencesame scaffold
(+/-)-Felodipine (2,3-dichlorophenyl-d3)
CAS1219795-30-8
pharmaceutical intermediate
Referencesame scaffold
3-Desethyl-3-(2-aminoethyl) aminoethoxy Amlodipine
CAS2923811-73-6
pharmaceutical intermediate
Safety Reference
Danger
H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H371May cause damage to organs
Identifiers
IUPAC Name
5-O-(butanoyloxymethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey
KPBZROQVTHLCDU-UHFFFAOYSA-N
SMILES
CCCC(=O)OCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
Synonyms (31)
- Clevidipine (USAN/INN)
- CLEVIDIPINE [MART.]
- Clevelox
- Clevidepine
- Clevidepine butyrate
- Clevidipine
- Clevidipine (Standard)
- Clevidipine butyrate
- Clevidipino
- Cleviprex
- Cleviprex (Clevidipine)
- Cleviprex (TN)
- H 324/38
- clevidipinum
- clevipidine
- rac-Clevidipine