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Home/Compounds/Pharmaceutical Intermediate/(R)-(+)-Propylene carbonate
C4H6O3
102.09 g/mol
Pharmaceutical IntermediateWarning

(4R)-4-methyl-1,3-dioxolan-2-one

CAS16606-55-6EC437-320-9
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a chiral cyclic carbonate. It serves as a key intermediate in the manufacturing of tenofovir disoproxil fumarate, an antiviral pharmaceutical.

Pharmaceutical intermediate for tenofovir disoproxil fumarate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

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ReferenceSame Category

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Referencestereoisomer of

(S)-1,2-Propanediol carbonate

CAS51260-39-0

cyclic carbonate solvent

Referencestereoisomer of

Propylene carbonate

CAS108-32-7

Solvent in industrial manufacturing

Referencesame scaffold

4-Fluoro-1,3-dioxolan-2-one

CAS114435-02-8

lithium ion battery additive

Referencesame scaffold

4,5-dichloro-4,5-dimethyl-1,3-dioxolan-2-one

CAS129482-56-0

research compound

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for (4R)-4-methyl-1,3-dioxolan-2-one (CAS 16606-55-6) is 2920.90.

HS code (international, 6-digit)

2920.90

EU CN code (8-digit)

2920 90 10

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(4R)-4-methyl-1,3-dioxolan-2-one

InChIKey

RUOJZAUFBMNUDX-GSVOUGTGSA-N

SMILES

C[C@@H]1COC(=O)O1

Synonyms (12)
  • (R)-(+)-Propylene carbonate
  • (R)-1,2-PROPYLENE CARBONATE
  • (S)-(-)-Propylene carbonate
  • Propylene carbonate, (R)-

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