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Home/Compounds/API/Ezetimibe
C24H21F2NO3
409.4 g/mol
APIWarning

Ezetimibe

CAS163222-33-1EC682-606-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Ezetimibe is an active pharmaceutical ingredient that functions as a cholesterol absorption inhibitor. It is used to lower total plasma cholesterol by inhibiting the intestinal absorption of cholesterol.

active pharmaceutical ingredient for cholesterol managementpharmaceutical raw material for antilipemic formulations

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.89

(3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one

CAS302781-98-2

pharmaceutical intermediate

ReferenceSame Category

Ceritinib D7

CAS1632484-77-5

pharmaceutical raw material

ReferenceSame Category

Sitafloxacin hydrate (2:3)

CAS163253-35-8

pharmaceutical raw material

ReferenceSame Category

((plusmn))-Zanubrutinib

CAS1633350-06-7

pharmaceutical raw material

ReferenceSame Category

Teriflunomide

CAS163451-81-8

pharmaceutical raw material

Referencestereoisomer of

(4S)-1-(4-Fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one

CAS163380-16-3

pharmaceutical raw material

Safety Reference

Environmental Hazard
Environmental Hazard
Warning
H410Very toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Ezetimibe (CAS 163222-33-1) is 2933.79.

HS code (international, 6-digit)

2933.79

EU CN code (8-digit)

2933 79 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one

InChIKey

OLNTVTPDXPETLC-XPWALMASSA-N

SMILES

C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O

Synonyms (39)
  • H56
  • Ezetimibe (JAN/USP/INN)
  • Ezetimibe, United States Pharmacopeia (USP)
  • 58235, SCH
  • EZETIMIBE [MART.]
  • Ezedoc
  • Ezetimibe
  • Ezetimibe (Standard)
  • Ezetimibe (Zetia)
  • Ezetimibe - Bio-X trade mark
  • Ezetimibe, >=98% (HPLC)
  • Ezetrol
  • K-924 component Ezetimibe
  • NEXLIZET COMPONENT EZETIMIBE
  • ROSZET COMPONENT EZETIMIBE
  • Sch 58235
  • VYTORIN COMPONENT EZETIMIBE
  • Zetia
  • Zetia (TN)
  • Zient
  • ezetimib
  • ezetimiba
  • ezetimibe anhydrate
  • ezetimibum

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