This compound is a chiral azetidinone derivative used as a pharmaceutical intermediate in the manufacturing of ezetimibe, a cholesterol-lowering agent. It features a 2-azetidinone core with fluorophenyl and benzyloxyphenyl substituents, reflecting its role in the synthesis of this active pharmaceutical ingredient.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)azetidin-2-one
pharmaceutical intermediate
(3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one
pharmaceutical intermediate
(3,4-Difluorophenyl)methanesulfonyl chloride
pharmaceutical intermediate
(R)-Boc-Nipecotic acid
pharmaceutical intermediate
(3R,4R)-(-)-1-Benzyl-3,4-pyrrolidinediol
pharmaceutical intermediate
3,3-Difluoropyrrolidine hydrochloride
pharmaceutical intermediate
(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-phenylmethoxyphenyl)azetidin-2-one
KEYVFYMGVLFXQK-DYIKCSJPSA-N
C1=CC=C(C=C1)COC2=CC=C(C=C2)[C@@H]3[C@H](C(=O)N3C4=CC=C(C=C4)F)CC[C@@H](C5=CC=C(C=C5)F)O
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