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Home/Compounds/API/Zerbaxa
C33H42N16O13S3
967 g/mol
API

Ceftolozane and tazobactam

CAS1613740-46-7
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Ceftolozane and tazobactam is a fixed-dose combination antibiotic compound used as an active pharmaceutical ingredient in the manufacture of medications. It combines a cephalosporin antibiotic with a beta-lactamase inhibitor, studied for infections caused by gram-negative bacteria resistant to conventional antibiotics.

pharmaceutical raw material for combination antibiotic preparationscomponent in manufacturing treatments for complicated urinary tract infectionscomponent in manufacturing treatments for complicated intra-abdominal infections

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Referencestereoisomer of

Ceftolozane sulfate

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Identifiers
IUPAC Name

(6R,7R)-3-[[5-amino-4-(2-aminoethylcarbamoylamino)-1-methylpyrazol-2-ium-2-yl]methyl]-7-[[(2E)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;(2S,3S)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

InChIKey

GRHWKSLBMDQBQW-KZVOOCJBSA-N

SMILES

C[C@@]1([C@@H](N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3.CC(C)(C(=O)O)O/N=C(\C1=NSC(=N1)N)/C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC(=C(N4C)N)NC(=O)NCCN)C(=O)[O-]

Synonyms (6)
  • Ceftolozane and tazobactam
  • Tazobactam and Ceftolozane
  • Zerbaxa
  • ceftolozane & tazobactam