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Home/Compounds/Pharmaceutical Intermediate/PyAOP reagent
C17H27F6N7OP2
521.4 g/mol
Pharmaceutical IntermediateWarning

PyAOP

CAS156311-83-0
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

PyAOP is a reagent used in peptide synthesis to form amide bonds from carboxylic acids and amines. It is a derivative of the HOAt family of amide bond forming reagents and is typically prepared from 1-hydroxy-7-azabenzotriazole (HOAt) under basic conditions.

peptide synthesis reagentamide bond formation in organic synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

(R)-3-(NAPHTHALEN-1-YLOXY)-1-PHENYLPROPAN-1-OL

CAS156453-53-1

pharmaceutical intermediate

ReferenceSame Category

6-(Dimethoxymethyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid

CAS156459-20-0

pharmaceutical intermediate

ReferenceSame Category

3,5-Difluorophenylboronic acid

CAS156545-07-2

pharmaceutical intermediate

ReferenceSame Category

3-Benzyloxybenzeneboronic acid

CAS156682-54-1

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

tripyrrolidin-1-yl(triazolo[4,5-b]pyridin-3-yloxy)phosphanium hexafluorophosphate

InChIKey

CBZAHNDHLWAZQC-UHFFFAOYSA-N

SMILES

C1CCN(C1)[P+](N2CCCC2)(N3CCCC3)ON4C5=C(C=CC=N5)N=N4.F[P-](F)(F)(F)(F)F

Synonyms (15)
  • PYAOP REAGENT
  • PyAOP

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