C14H9ClF3NO2
315.67 g/mol
APIDanger
Efavirenz
CAS154598-52-4
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Efavirenz is a chemical compound used as an active pharmaceutical ingredient in the manufacture of antiretroviral medications. It is known for its role as a non-nucleoside reverse transcriptase inhibitor, contributing to the suppression of viral replication in HIV treatment regimens.
anti-HIV agentsreverse transcriptase inhibitors
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
ReferenceSame Category
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ReferenceSame Category
Octreotide Impurity 13
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Referencestereoisomer of
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-
CAS177530-93-7
pharmaceutical raw material
Safety Reference
Danger
H302Harmful if swallowed
H319Causes serious eye irritation
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Customs Tariff Classification
The international HS code for Efavirenz (CAS 154598-52-4) is 2934.99.
HS code (international, 6-digit)
2934.99
EU CN code (8-digit)
2934 99 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
InChIKey
XPOQHMRABVBWPR-ZDUSSCGKSA-N
SMILES
C1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
Synonyms (76)
- EFV
- Efavirenz (JAN/USP/INN)
- Efavirenz, United States Pharmacopeia (USP)
- (Rac)-Efavirenz
- (S)-Efavirenz
- 1ikv
- 1ikw
- ATRIPLA COMPONENT EFAVIRENZ
- DMP-266; Efavirenz
- EFAVIRENZ [MART.]
- EFV & IFNL1
- EFV & IFNL2
- EFV & IFNL3
- EFV & IL-28A
- EFV & IL-28B
- EFV & IL-29
- EFV & Interferon lambda-1
- EFV & Interferon lambda-2
- EFV & Interferon lambda-3
- EFV & Interleukin 28A
- EFV & Interleukin 28B
- EFV & Interleukin 29
- EFV & PLGA
- Efavirenz & IFNL1
- Efavirenz & IFNL2
- Efavirenz & IFNL3
- Efavirenz & IL-28A
- Efavirenz & IL-28B
- Efavirenz & IL-29
- Efavirenz & Interleukin 28A
- Efavirenz & Interleukin 28B
- Efavirenz & Interleukin 29
- Efavirenz & PLGA
- Efavirenz (Standard)
- Efavirenz - Bio-X trade mark
- Efavirenz RS
- Efavirenz teva
- Efavirenz, >=98% (HPLC)
- Efavirenzum
- Eravirenz
- L-743,726
- Met-SDF-1.beta. & Efavirenz
- Stocrin
- Strocin (TM)
- Sustiva
- Sustiva (TM)
- Sustiva (TN)
- Sustiva 600
- TELURA COMPONENT EFAVIRENZ
- Viraday
- efavirenz
- efavirenz, (S)-
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