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Home/Compounds/Pharmaceutical Intermediate/9-(2-Deoxypentofuranosyl)-2-fluoro-6-[2-(trimethylsilyl)ethoxy]-9H-purine
C15H23FN4O4Si
370.45 g/mol
Pharmaceutical Intermediate

2-FTMSE-DI

CAS151900-41-3
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

2-FTMSE-DI is a protected nucleoside intermediate used in pharmaceutical manufacturing. It features a purine base with a fluorine atom and a trimethylsilylethoxy protecting group, linked to a modified ribose moiety.

Protected nucleoside intermediate for pharmaceutical synthesisBuilding block in the production of nucleoside analogs

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ApplicationSame Use

Triethylamine 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoate

CAS2622236-65-9

pharmaceutical intermediate

ReferenceSame Category

2-Chloro-4-fluorobenzylamine

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N,N'-Di-Boc-1H-pyrazole-1-carboxamidine

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ReferenceSame Category

(S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone

CAS152305-23-2

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ReferenceSame Category

(3R,4R)-4-fluoropyrrolidin-3-ol hydrochloride

CAS1523530-25-7

pharmaceutical intermediate

Identifiers
IUPAC Name

(2R,3S,5R)-5-[2-fluoro-6-(2-trimethylsilylethoxy)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol

InChIKey

VHGLFFIEVNCJDK-HBNTYKKESA-N

SMILES

C[Si](C)(C)CCOC1=NC(=NC2=C1N=CN2[C@H]3C[C@@H]([C@H](O3)CO)O)F

Synonyms (6)
  • 2-FTMSE-DI

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