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Home/Compounds/API/Tolvaptan
C26H25ClN2O3
448.9 g/mol
APIWarning

Tolvaptan

CAS150683-30-0
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Tolvaptan is a racemic compound consisting of equal amounts of (R)- and (S)-tolvaptan. It acts as a selective vasopressin V2 receptor antagonist and is used in the management of certain types of hyponatremia and to slow the progression of kidney disease in autosomal dominant polycystic kidney disease.

vasopressin V2 receptor antagonistaquaretic agent

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongForm Family

Tolvaptan sodium phosphate

CAS942619-79-6

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.81

N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

CAS1432725-23-9

research compound

ReferenceSame Category

Oxybutynin chloride

CAS1508-65-2

pharmaceutical raw material

ReferenceSame Category

Tropicamide

CAS1508-75-4

pharmaceutical raw material

ReferenceSame Category

Procyclidine hydrochloride

CAS1508-76-5

pharmaceutical raw material

ReferenceSame Category

Ezogabine dihydrochloride

CAS150812-13-8

pharmaceutical raw material

Referencesame scaffold

Mozavaptan

CAS137975-06-5

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Warning
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H413May cause long lasting harmful effects to aquatic life

Customs Tariff Classification

The international HS code for Tolvaptan (CAS 150683-30-0) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide

InChIKey

GYHCTFXIZSNGJT-UHFFFAOYSA-N

SMILES

CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C

Synonyms (24)
  • (R)-(+)-Tolvaptan
  • OPC-41061(TOLVAPTAN)
  • TOLVAPTAN [MART.]
  • Tolvaptan
  • Tolvaptan (OPC-41061)
  • Tolvaptan (Standard)
  • Tolvaptan - Bio-X trade mark
  • benzazepine derivative, 32
  • jinarc
  • tolvaptanum

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