C26H25ClN2O3
448.9 g/mol
APIWarning
Tolvaptan
CAS150683-30-0
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Tolvaptan is a racemic compound consisting of equal amounts of (R)- and (S)-tolvaptan. It acts as a selective vasopressin V2 receptor antagonist and is used in the management of certain types of hyponatremia and to slow the progression of kidney disease in autosomal dominant polycystic kidney disease.
vasopressin V2 receptor antagonistaquaretic agent
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 150683-30-0
Related Compounds
StrongForm Family
Tolvaptan sodium phosphate
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SimilarStructure SimilarSimilarity 0.81
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Referencesame scaffold
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Safety Reference
Warning
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name
N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
InChIKey
GYHCTFXIZSNGJT-UHFFFAOYSA-N
SMILES
CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C
Synonyms (24)
- (R)-(+)-Tolvaptan
- OPC-41061(TOLVAPTAN)
- TOLVAPTAN [MART.]
- Tolvaptan
- Tolvaptan (OPC-41061)
- Tolvaptan (Standard)
- Tolvaptan - Bio-X trade mark
- benzazepine derivative, 32
- jinarc
- tolvaptanum