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Home/Compounds/Research Reagent/Archaeosine
C12H16N6O5
324.29 g/mol
Research Reagent

Archaeosine

CAS148608-52-0
Category
Research Reagent
Compound Class
Natural Product
Primary Use
Research Compound

Archaeosine is a modified ribonucleoside found in archaeal transfer RNA, specifically at position 15 of the dihydrouridine loop. It features a 7-formamidino-7-deazaguanine nucleobase and is notable for being a post-transcriptional modification unique to archaea, not occurring in bacterial or eukaryotic tRNA.

Post-transcriptional modification in archaeal tRNAResearch reagent for studying archaeal RNA modification

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

2-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide

InChIKey

PEMQXWCOMFJRLS-RPKMEZRRSA-N

SMILES

C1=C(C2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N)C(=N)N

Synonyms (10)
  • 7-Formamido-7-deazaguanosine
  • Archaeosine
  • G*