C23H23N7O5
477.5 g/mol
APIDanger
Pralatrexate
CAS146464-95-1
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Pralatrexate is a pharmaceutical compound used as an active pharmaceutical ingredient in the production of medications. It is primarily utilized in the manufacturing of drugs for relapsed or refractory peripheral T-cell lymphoma.
pharmaceutical manufacturingactive pharmaceutical ingredient for oncology drugs
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 146464-95-1
Related Compounds
ReferenceSame Category
(2S,3Z)-5-{[(2R,3R,5S,6S)-6-{(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methylpenta-2,4-dien-1-yl}-2,5-dimethyltetrahydro-2H-pyran-3-yl]amino}-5-oxopent-3-en-2-yl acetate
CAS146478-72-0
pharmaceutical raw material
ReferenceSame Category
(2S,3Z)-5-{[(2R,3R,5S,6S)-2,5-dimethyl-6-{(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]penta-2,4-dien-1-yl}tetrahydro-2H-pyran-3-yl]amino}-5-oxopent-3-en-2-yl acetate
CAS146478-73-1
pharmaceutical raw material
ReferenceSame Category
Dantrolene sodium
CAS14663-23-1
pharmaceutical raw material
ReferenceSame Category
Ziprasidone
CAS146939-27-7
pharmaceutical raw material
Referencesame scaffold
2,4-Diamino-alpha-[4-(methoxycarbonyl)phenyl]-alpha-2-propynyl-6-pteridinepropanoic acid methyl ester
CAS146464-91-7
pharmaceutical intermediate
Safety Reference
Danger
H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
H340May cause genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
(2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid
InChIKey
OGSBUKJUDHAQEA-WMCAAGNKSA-N
SMILES
C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Synonyms (23)
- PDX
- Pralatrexate (JAN/USAN/INN)
- 146464-95-1 (racemic)
- Folotyn
- Folotyn (TN)
- PRALATREXATE [MART.]
- Pralatrexate
- Pralatrexate(Folotyn)
- Pralatrexte
- pralatrexato
- pralatrexatum