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Home/Compounds/Pharmaceutical Intermediate/(2R,5S)-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dione
C8H10N2O4S
230.24 g/mol
Pharmaceutical Intermediate

1-(2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dione, (2R,5S)-

CAS145986-07-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate featuring a pyrimidinedione core linked to an oxathiolane ring with a hydroxymethyl substituent. Its significance lies in its use as a building block for the synthesis of antiviral agents.

Pharmaceutical intermediate for antiviral researchLaboratory reagent for nucleoside analog synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione

InChIKey

BNVOMPQTQUUYHU-NKWVEPMBSA-N

SMILES

C1[C@H](O[C@H](S1)CO)N2C=CC(=O)NC2=O

Synonyms (15)
  • 2,4(1H,3H)-Pyrimidinedione, 1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)- (9CI); 1,3-Oxathiolane, 2,4(1H,3H)-pyrimidinedione deriv.; 1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4(1H,3H)-dione; Lamivudine Imp. J (EP)
  • Lamivudine EP Impurity J
  • LAMIVUDINE IMPURITY J
  • LAMIVUDINE-URACIL DERIVATIVE