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Home/Compounds/API/Ivosidenib
C28H22ClF3N6O3
583 g/mol
APIDanger

Ivosidenib

CAS1448347-49-6
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Ivosidenib is an active pharmaceutical ingredient that functions as an inhibitor of isocitrate dehydrogenase 1 (IDH1). It is used in the manufacturing of pharmaceutical products for research and development applications.

Isocitrate dehydrogenase 1 inhibitorAntineoplastic agent

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

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Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Danger
H302Harmful if swallowed
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure

Customs Tariff Classification

The international HS code for Ivosidenib (CAS 1448347-49-6) is 2933.79.

HS code (international, 6-digit)

2933.79

EU CN code (8-digit)

2933 79 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide

InChIKey

WIJZXSAJMHAVGX-DHLKQENFSA-N

SMILES

C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N

Synonyms (18)
  • Ivosidenib (JAN/USAN/INN)
  • Ivosidenib
  • Tibsovo
  • Tibsovo (TN)
  • US9850277, Compound 176
  • ivosidenibum

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