C28H22ClF3N6O3
583 g/mol
APIDanger
Ivosidenib
CAS1448347-49-6
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Ivosidenib is an active pharmaceutical ingredient that functions as an inhibitor of isocitrate dehydrogenase 1 (IDH1). It is used in the manufacturing of pharmaceutical products for research and development applications.
Isocitrate dehydrogenase 1 inhibitorAntineoplastic agent
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1448347-49-6
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Safety Reference
Danger
H302Harmful if swallowed
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
(2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide
InChIKey
WIJZXSAJMHAVGX-DHLKQENFSA-N
SMILES
C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
Synonyms (18)
- Ivosidenib (JAN/USAN/INN)
- Ivosidenib
- Tibsovo
- Tibsovo (TN)
- US9850277, Compound 176
- ivosidenibum