C19H19N3O3
337.4 g/mol
APIWarning
Voxelotor
CAS1446321-46-5
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Voxelotor is a pharmaceutical raw material that functions as a hemoglobin S polymerization inhibitor. It is investigated for use in the management of sickle cell disease through a novel mechanism distinct from other compounds in this area.
Compound used in pharmaceutical manufacturing for sickle cell disease researchInhibitor of hemoglobin S polymerization in laboratory studiesResearch compound for hemolytic anemia associated with sickle cell disease
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
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Safety Reference
Warning
H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects
Customs Tariff Classification
The international HS code for Voxelotor (CAS 1446321-46-5) is 2933.39.
HS code (international, 6-digit)
2933.39
EU CN code (8-digit)
2933 39 99
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
2-hydroxy-6-[[2-(2-propan-2-ylpyrazol-3-yl)-3-pyridinyl]methoxy]benzaldehyde
InChIKey
FWCVZAQENIZVMY-UHFFFAOYSA-N
SMILES
CC(C)N1C(=CC=N1)C2=C(C=CC=N2)COC3=CC=CC(=C3C=O)O
Synonyms (19)
- GBT440
- GTX-011
- Voxelotor (USAN)
- GBT-440(Voxelotor)
- Hemoglobin Modulators-1
- Oxbryta
- Oxbryta (TN)
- Voxelotor
- Voxelotor (GBT440)
- Voxelotor(GBT440, GTx011)
- Voxelotorum
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