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Home/Compounds/Research Reagent/DBCO-CONH-S-S-NHS ester
C28H27N3O6S2
565.7 g/mol
Research Reagent

DBCO-CONH-S-S-NHS ester

CAS1435934-53-4
Category
Research Reagent
Compound Class
Ester
Primary Use
Research Compound

DBCO-CONH-S-S-NHS ester is a heterobifunctional crosslinking reagent designed for click chemistry conjugation. It contains a DBCO (dibenzocyclooctyne) group for copper-free azide-alkyne cycloaddition and an NHS ester for amine coupling, linked by a cleavable disulfide bond.

bioconjugation of antibodies or proteins with azide-modified moleculesresearch reagent for site-specific labeling in biological systems

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 3-[2-[[4-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-4-oxobutanoyl]amino]ethyldisulfanyl]propanoate

InChIKey

RPNGUSKTYYIUDE-UHFFFAOYSA-N

SMILES

C1CC(=O)N(C1=O)OC(=O)CCSSCCNC(=O)CCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42

Synonyms (8)
  • DBCO-CONH-S-S-COONHS ester
  • DBCO-CONH-S-S-NHS ester
  • DBCO-S-S-NHS