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Home/Compounds/Pharmaceutical Intermediate/CARBAMIC ACID, N-[(1R)-2-[1,1'-BIPHENYL]-4-YL-1-(HYDROXYMETHYL)ETHYL]-, 1,1-DIMETHYLETHYL ESTER
C20H25NO3
327.4 g/mol
Pharmaceutical Intermediate

CARBAMIC ACID, N-[(1R)-2-[1,1'-BIPHENYL]-4-YL-1-(HYDROXYMETHYL)ETHYL]-, 1,1-DIMETHYLETHYL ESTER

CAS1426129-50-1EC810-281-9
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate used in the manufacturing of LCZ696, a drug substance. It is a chiral, protected amino alcohol featuring an aromatic biphenyl group.

Pharmaceutical intermediate for LCZ696 manufacturingLaboratory reagent in organic synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Environmental Hazard
Environmental Hazard
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name

tert-butyl N-[(2R)-1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate

InChIKey

TYQICOFAZDVKMK-GOSISDBHSA-N

SMILES

CC(C)(C)OC(=O)N[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)CO

Synonyms (17)
  • LCZ-696 Intermediate 39
  • LCZ696 InteMediate
  • Valsartan Impurity 26