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Home/Compounds/Pharmaceutical Intermediate/2,2-Dimethylpropanoic acid [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester
C16H26N5O6P
415.38 g/mol
Pharmaceutical Intermediate

((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)(ethoxy)phosphoryl)oxy)methyl pivalate

CAS142341-04-6
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a phosphorylated nucleotide derivative used as a prodrug intermediate in the manufacturing of adefovir, an antiviral agent. It features a purine base linked to a phosphonate ester with a pivaloyloxymethyl protecting group, contributing to its role in pharmaceutical synthesis.

prodrug intermediate for adefovirpharmaceutical intermediate in antiviral drug manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.93

Adefovir dipivoxil

CAS142340-99-6

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.79

Adefovir monopivoxil

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pharmaceutical raw material

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6-(Boc-amino)hexyl bromide

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pharmaceutical intermediate

ReferenceSame Category

N-(5-Bromo-6-methylpyridin-2-yl)acetamide

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pharmaceutical intermediate

ReferenceSame Category

Methyl [E]-2-[3-(S)-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoate

CAS142569-69-5

pharmaceutical intermediate

ReferenceSame Category

2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol

CAS142569-70-8

pharmaceutical intermediate

Identifiers
IUPAC Name

[2-(6-aminopurin-9-yl)ethoxymethyl-ethoxyphosphoryl]oxymethyl 2,2-dimethylpropanoate

InChIKey

NOZLVTCICOSPFI-UHFFFAOYSA-N

SMILES

CCOP(=O)(COCCN1C=NC2=C(N=CN=C21)N)OCOC(=O)C(C)(C)C

Synonyms (8)
  • Adefovir Impurity E
  • Mono-POM Ethyl Adefovir