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Home/Compounds/Pharmaceutical Intermediate/(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol
C52H49N5O5
824 g/mol
Pharmaceutical Intermediate

(1S,2S,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-9H-purin-9-yl)-2-((benzyloxy)methyl)cyclopentanol

CAS142217-78-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a synthetic intermediate used in the preparation of entecavir, a nucleoside analogue pharmaceutical active against hepatitis B virus. It features multiple aromatic rings and protective functional groups typical for multi-step organic synthesis.

Manufacturing intermediate for entecavirBuilding block in nucleoside analogue research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(1S,2S,3S,5S)-5-[2-[[(4-methoxyphenyl)-diphenylmethyl]amino]-6-phenylmethoxypurin-9-yl]-3-phenylmethoxy-2-(phenylmethoxymethyl)cyclopentan-1-ol

InChIKey

ZLWZEFPIJWNPCO-ABKHIKNWSA-N

SMILES

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC4=NC5=C(C(=N4)OCC6=CC=CC=C6)N=CN5[C@H]7C[C@@H]([C@H]([C@@H]7O)COCC8=CC=CC=C8)OCC9=CC=CC=C9

Synonyms (10)
  • Entecavir Impurity 1
  • Entecavir Impurity 12
  • Entecavir Impurity 79
  • Entecavir-?5