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Home/Compounds/Pharmaceutical Intermediate/16α-hydroxyprednisolone
C21H28O6
376.4 g/mol
Pharmaceutical IntermediateDanger

16alpha-Hydroxyprednisolone

CAS13951-70-7EC237-731-1
Category
Pharmaceutical Intermediate
Compound Class
Steroid
Primary Use
Pharmaceutical Intermediate

16alpha-Hydroxyprednisolone is a corticosteroid compound used as a pharmaceutical raw material in the manufacturing of pharmaceutical intermediates. It is characterized by a polycyclic structure with multiple hydroxyl groups and a hydroxyacetyl side chain, indicating its role in steroid-based synthesis.

pharmaceutical intermediateraw material for corticosteroid synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.84

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Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Danger
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H373May cause damage to organs through prolonged or repeated exposure

Customs Tariff Classification

The international HS code for 16alpha-Hydroxyprednisolone (CAS 13951-70-7) is 2914.40.

HS code (international, 6-digit)

2914.40

EU CN code (8-digit)

2914 40 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(8S,9S,10R,11S,13S,14S,16R,17S)-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

InChIKey

SEKYBDYVXDAYPY-ILNISADRSA-N

SMILES

C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@]34C)O

Synonyms (22)
  • OH-PRED
  • 11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione; Budesonide Imp. A (EP); 16alpha-Hydroxyprednisolone; Budesonide Impurity A
  • BUDESONIDE IMPURITY A (EP IMPURITY)
  • Budesonide EP Impurity A
  • Budesonide EP Impurity A (16-alpha-Hydroxy-Prednisolone)
  • 16alpha-Hydroxyprednisolone
  • 16alpha-Hydroxyprednisonlone
  • 16|A-Hydroxyprednisolone
  • BUDESONIDE IMPURITY A

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