C17H11F6N7O
443.3 g/mol
APIWarning
Selinexor
CAS1393477-72-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Selinexor is a member of the triazole class of compounds that inhibits the nuclear export protein XPO1. It is used as an active pharmaceutical ingredient in pharmaceutical manufacturing and research applications.
Nuclear export inhibitorAntineoplastic agentApoptosis inducer
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1393477-72-9
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Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
Identifiers
IUPAC Name
(Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide
InChIKey
DEVSOMFAQLZNKR-RJRFIUFISA-N
SMILES
C1=CN=C(C=N1)NNC(=O)/C=C\N2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
Synonyms (20)
- Selinexor (USAN/INN)
- KPT330;Selinexor
- Nexpovio
- SINE KPT-330
- Selinexor
- Selinexor (KPT-330)
- Selinexor (Standard)
- Selinexor free base
- Xpovio
- Xpovio (TN)
- compound 70
- selinexorum