Home/Compounds/Pharmaceutical Intermediate/5-methyl-2-((2-nitrophenyl)amino)-3-thiophenecarbonitrile
C12H9N3O2S
259.29 g/mol
Pharmaceutical IntermediateWarning
5-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile
CAS138564-59-7EC421-300-1
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a thiophene-based aromatic amine featuring a nitrile group and a nitro-substituted phenylamino moiety. It is primarily recognized as a pharmaceutical intermediate used in the manufacturing of olanzapine.
pharmaceutical intermediate for olanzapine synthesisresearch compound for polymorphic studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 138564-59-7
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Referencesame scaffold
2-(2-Aminoanilino)-5-methylthiophene-3-carbonitrile
CAS873895-41-1
pharmaceutical intermediate
Safety Reference
Warning
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H319Causes serious eye irritation
Identifiers
IUPAC Name
5-methyl-2-(2-nitroanilino)thiophene-3-carbonitrile
InChIKey
NPXUFPFFHANGDL-UHFFFAOYSA-N
SMILES
CC1=CC(=C(S1)NC2=CC=CC=C2[N+](=O)[O-])C#N
Synonyms (18)
- MNPATCN
- ROY-OP
- Olanzapine EP Impurity A
- Olanzapine EP Impurity A; Olanzapine USP Rc A
- Olanzapine Imp. A (EP); Olanzapine USP Related Compound A; Olanzapine USP RC A; 5-Methyl-2-[(2-nitrophenyl)amino]thiophene-3-carbonitrile; Olanzapine Related Compound A; Olanzapine Impurity A
- OLANZAPINE IMPURITY A
- Olanzapine impurity A CRS
- ROY thiophenecarbonitrile