Gadobutrol is a second-generation, non-ionic macrocyclic gadolinium-based contrast agent (GBCA) used in magnetic resonance imaging (MRI). It is formulated at a higher gadolinium concentration than other GBCAs, requiring a smaller injection volume, and the macrocyclic structure is associated with a lower risk of nephrogenic systemic fibrosis (NSF).
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Calcium 2,2'-[7-(carboxymethyl)-10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4-diyl]diacetate
pharmaceutical intermediate
Gadobutrol
pharmaceutical raw material
2,2'-(4,10-bis(1,3,4-Trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetic acid
pharmaceutical intermediate
2,2'-(4,10-Bis(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetic acid tetrahydrochloride
pharmaceutical raw material
Agomelatine
pharmaceutical raw material
Levofloxacin hemihydrate
pharmaceutical raw material
Tropifexor
pharmaceutical raw material
Irbesartan
pharmaceutical raw material
2-[4,10-bis(carboxylatomethyl)-7-[(2R,3S)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetrazacyclododec-1-yl]acetate;gadolinium(3+)
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C1CN(CCN(CCN(CCN1CC(=O)[O-])CC(=O)[O-])[C@H](CO)[C@@H](CO)O)CC(=O)[O-].[Gd+3]
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