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Home/Compounds/Pharmaceutical Intermediate/(3S,4R)-3-[(1R)-1-Hydroxyethyl]-4-[(1R)-1-methyl-3-diazo-3-(4-nitrobenzyloxycarbonyl)-2-oxopropyl]azetidin-2-one
C17H18N4O7
390.3 g/mol
Pharmaceutical Intermediate

(R)-4-Nitrobenzyl 2-diazo-4-((2R,3S)-3-((R)-1-hydroxyethyl)-4-oxoazetidin-2-yl)-3-oxopentanoate

CAS137391-68-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate specifically used in the manufacturing of the carbapenem antibiotic meropenem. It features a complex stereochemistry with an azetidinone ring and a diazo group, characteristic of advanced intermediates in beta-lactam synthesis.

pharmaceutical intermediate for meropenem productionlaboratory reagent for drug research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

(R)-4-Nitrobenzyl 2-diazo-4-((2R,3S)-3-((R)-1-hydroxyethyl)-4-oxoazetidin-2-yl)-3-oxopentanoate

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ReferenceSame Category

7-(1-(((Tert-butoxycarbonyl)amino)methyl)cyclohexyl)-2-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid

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pharmaceutical intermediate

Identifiers
IUPAC Name

(4-nitrophenyl)methyl (4R)-2-diazo-4-[(2R,3S)-3-[(1R)-1-hydroxyethyl]-4-oxoazetidin-2-yl]-3-oxopentanoate

InChIKey

FDXUXRZSNNSUGD-NRMKKVEVSA-N

SMILES

C[C@H]([C@@H]1[C@H](NC1=O)[C@@H](C)C(=O)C(=[N+]=[N-])C(=O)OCC2=CC=C(C=C2)[N+](=O)[O-])O

Synonyms (18)
  • Etapenem lmpurity 40
  • Meropenem Impurity 13

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