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Home/Compounds/Pharmaceutical Intermediate/Boc-L-glutamic acid 5-tert-butyl ester
C14H25NO6
303.35 g/mol
Pharmaceutical IntermediateWarning

(2S)-5-(tert-butoxy)-2-{[(tert-butoxy)carbonyl]amino}-5-oxopentanoic acid

CAS13726-84-6EC695-119-3
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid intermediate used in pharmaceutical manufacturing. It features tert-butoxycarbonyl (Boc) protecting groups on both the amino and carboxyl functionalities, making it suitable for peptide synthesis and laboratory research.

protected amino acid intermediate for peptide synthesisreagent in pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.85

Boc-L-glutamic acid 5-methyl ester

CAS45214-91-3

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.79

Boc-L-Glutamic acid

CAS2419-94-5

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.76

N-Acetyl-L-glutamic acid 5-tert-butyl ester

CAS84192-88-1

research compound

SimilarStructure SimilarSimilarity 0.74

Boc-L-Glutamine

CAS13726-85-7

pharmaceutical intermediate

ApplicationSame Use

Boc-O-tert-butyl-L-serine dicyclohexylamine salt

CAS18942-50-2

pharmaceutical intermediate

ApplicationSame Use

BOC-ARG(BOC)2-OH

CAS108787-91-3

pharmaceutical intermediate

ApplicationSame Use

N-Carbobenzyloxy-L-glutamine

CAS2650-64-8

pharmaceutical intermediate

ApplicationSame Use

N-Cbz-L-Isoleucine

CAS3160-59-6

pharmaceutical intermediate

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

Read more

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2S)-5-[(2-methylpropan-2-yl)oxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid

InChIKey

YGSRAYJBEREVRB-VIFPVBQESA-N

SMILES

CC(C)(C)OC(=O)CC[C@@H](C(=O)O)NC(=O)OC(C)(C)C

Synonyms (16)
  • Boc-Glu(OtBu)
  • Boc-Glu(OtBu)-OH
  • Boc-L-Glu(OtBu)-OH

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