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Home/Compounds/Pharmaceutical Intermediate/4-[4-(Hydroxymethyl)-3-methoxyphenoxy]butanoic acid
C12H16O5
240.25 g/mol
Pharmaceutical IntermediateWarning

4-(4-HYDROXYMETHYL-3-METHOXYPHENOXY)-BUTYRIC ACID

CAS136849-75-7EC625-092-5
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

4-(4-Hydroxymethyl-3-methoxyphenoxy)butanoic acid is a pharmaceutical intermediate used as an HMPB linker in solid-phase peptide synthesis. This compound serves as a cleavable anchor for attaching peptides to a solid support during automated synthesis.

HMPB linker for solid-phase peptide synthesispharmaceutical intermediate for peptide manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 136849-75-7

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ReferenceSame Category

2-{(2S)-2-Hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl}-1H-isoindole-1,3(2H)-dione

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

4-[4-(hydroxymethyl)-3-methoxyphenoxy]butanoic acid

InChIKey

HXOYWJCDYVODON-UHFFFAOYSA-N

SMILES

COC1=C(C=CC(=C1)OCCCC(=O)O)CO

Synonyms (8)
  • HMPB
  • hmpba