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Home/Compounds/API/(3aS)-palonosetron hydrochloride
C19H25ClN2O
332.9 g/mol
APIWarning

Palonosetron hydrochloride

CAS135729-62-3
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Palonosetron hydrochloride is a pharmaceutical raw material used as an antiemetic active ingredient. It functions as a 5-HT3 antagonist and is primarily employed in the manufacturing of medications to prevent and treat chemotherapy-induced nausea and vomiting.

Active pharmaceutical ingredient for antiemetic formulationsPharmaceutical intermediate for CINV prevention and treatment compounds

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 135729-62-3

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Related Compounds

ApplicationSame Use

Diphenidol hydrochloride

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ApplicationSame Use

Alizapride hydrochloride

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pharmaceutical raw material

ReferenceSame Category

Phenazopyridine hydrochloride

CAS136-40-3

pharmaceutical raw material

ReferenceSame Category

Tetracaine hydrochloride

CAS136-47-0

pharmaceutical raw material

ReferenceSame Category

4-hexylresorcinol

CAS136-77-6

pharmaceutical raw material

Referencestereoisomer of

Palonosetron hydrochloride

CAS135755-51-0

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer
Identifiers
IUPAC Name

(3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride

InChIKey

OLDRWYVIKMSFFB-SSPJITILSA-N

SMILES

C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@@H]4CN5CCC4CC5.Cl

Synonyms (33)
  • Palonosetron hydrochloride (JAN/USP)
  • Palonosetron hydrochloride, United States Pharmacopeia (USP)
  • Aloxi
  • Aloxi (TN)
  • Onicit
  • Onicita
  • PALONOSETRON HCl
  • Palonocetron hydrochloride
  • Palonosetron hydrochloride
  • Palonsetron hydrochloride
  • Paloxi
  • RS 25259-197
  • posfrea