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Home/Compounds/Pharmaceutical Intermediate/Trityllosartan
C41H37ClN6O
665.2 g/mol
Pharmaceutical Intermediate

Trityllosartan

CAS133909-99-6EC412-420-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

Trityllosartan is a chemical compound used as a pharmaceutical intermediate, specifically in the synthesis of the antihypertensive drug losartan. Its structure features a tetrazole ring with a trityl protecting group, which is characteristic of intermediates used in sartan-class drug manufacturing.

pharmaceutical intermediate for sartan-class drug synthesislaboratory research compound

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.72

[2-Butyl-4-chloro-1-[(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-1H-imidazol-5-yl]methanol

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Referencesame scaffold

N-Trityl Olmesartan Ethyl Ester

CAS172875-59-1

pharmaceutical intermediate

Safety Reference

Environmental Hazard
Environmental Hazard
H413May cause long lasting harmful effects to aquatic life

Customs Tariff Classification

The international HS code for Trityllosartan (CAS 133909-99-6) is 2933.29.

HS code (international, 6-digit)

2933.29

EU CN code (8-digit)

2933 29 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

[2-butyl-5-chloro-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol

InChIKey

QQPGGBNMTNDKEY-UHFFFAOYSA-N

SMILES

CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN(N=N4)C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)CO)Cl

Synonyms (17)
  • LOSARTAN POTASSIUM IMPURITY H(EP IMPURITY)
  • Losartan EP Impurity H
  • Losartan Potassium Imp. H (EP); Losartan Imp. H (EP); [2-Butyl-4-chloro-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methanol; Losartan Potassium Impurity H; Losartan Impurity H
  • Losartan potassium impurity H
  • N-Trityllosartan
  • N2-Trityllosartan
  • Trityllosartan

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