C26H41N3O5
475.6 g/mol
Research ReagentWarning
Z-Leu-leu-leu-al
CAS133407-82-6EC849-040-8
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound
Z-Leu-leu-leu-al (N-benzoxycarbonyl-L-leucyl-L-leucyl-L-leucinal) is a tripeptide aldehyde compound primarily used as a research reagent in proteasome inhibition studies. Its structure features three leucine residues, an aldehyde group, and a benzyloxycarbonyl protecting group, contributing to its role as a laboratory tool for investigating protein degradation pathways.
Proteasome inhibitor research reagent
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
ReferenceSame Category
1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22-hexaoxa-4-azapentacosan-25-oic acid
CAS1334177-79-5
research compound
ReferenceSame Category
1-Maleimido-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-aza-hentriacontan-31-oic acid
CAS1334177-86-4
research compound
ReferenceSame Category
Alpha-Benzyloxycarbonylamino-24(ethylene glycol)-omega-propionic acid
CAS1334177-88-6
research compound
ReferenceSame Category
O-2-(1,3-Dioxoisoindolin-2-yl)ethyl S-methyl carbonodithioate
CAS1334418-35-7
research compound
Related Reading
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for Z-Leu-leu-leu-al (CAS 133407-82-6) is 2924.29.
HS code (international, 6-digit)
2924.29
EU CN code (8-digit)
2924 29 70
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
InChIKey
TZYWCYJVHRLUCT-VABKMULXSA-N
SMILES
CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1
Synonyms (46)
- Z-LLL
- Z-LLL-H
- (R)-MG132
- (S)-MG132
- Cbz-L-Leu-L-Leu-L-Leu-CHO
- Cbz-L-Leu-L-Leu-L-Leu-H
- Cbz-Leu-Leu-Leu-H
- Cbz-Leu-Leu-Leucinal
- Lll cpd
- MG-132 [Z-Leu- Leu-Leu-CHO]
- MG-132?
- Proteasome Inhibitor MG-132
- Z-L-leu-L-leu-L-leu-H
- Z-LLL-CHO
- Z-Leu-Leu-Leu-H
- Z-Leu-Leu-Leu-H (aldehyde)
- Z-Leu-leu-leu-al
- Z-Leu-leu-leucinal
- Zlllal
- carbobenzoxy-Leu-Leu-leucinal
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