C38H32N2O5
596.7 g/mol
Pharmaceutical Intermediate
Fmoc-Asn(Trt)-OH
CAS132388-59-1EC603-578-8
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
Fmoc-Asn(Trt)-OH is a protected asparagine derivative used as a building block in solid-phase peptide synthesis with the Fmoc strategy. It features a trityl (Trt) protecting group on the side-chain amide and a fluorenylmethoxycarbonyl (Fmoc) group on the alpha-amine, enabling selective deprotection during peptide assembly.
Peptide synthesis intermediateBuilding block for Fmoc-based solid-phase peptide synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 132388-59-1
Related Compounds
SimilarStructure SimilarSimilarity 0.81
N-Fmoc-N'-trityl-D-glutamine
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SimilarStructure SimilarSimilarity 0.81
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Referencestereoisomer of
N-(9-Fluorenylmethyloxycarbonyl)-N'-trityl-D-asparagine
CAS180570-71-2
pharmaceutical intermediate
Safety Reference
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoic acid
InChIKey
KJYAFJQCGPUXJY-UMSFTDKQSA-N
SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)C[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
Synonyms (15)
- Fmoc-Asn(Trt)-OH
- Fmoc-L-Asn(Trt)-OH
- N-Fmoc-N4-trityl-L-Asparagine