C22H28O4
356.5 g/mol
APIWarning
Vamorolone
CAS13209-41-1EC236-177-8
Category
API
Compound Class
Steroid
Primary Use
Pharmaceutical Raw Material
Vamorolone is a synthetic corticosteroid compound that functions as a glucocorticoid receptor agonist. It is approved by the FDA as an anti-inflammatory active pharmaceutical ingredient for use in patients with Duchenne muscular dystrophy aged 2 years and older.
pharmaceutical raw material for anti-inflammatory therapyimmunosuppressive agentglucocorticoid receptor agonist
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 13209-41-1
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Safety Reference
Warning
H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
Identifiers
IUPAC Name
(8S,10S,13S,14S,16R,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one
InChIKey
ZYTXTXAMMDTYDQ-DGEXFFLYSA-N
SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC[C@@]2([C@]1(C(=O)CO)O)C)C
Synonyms (23)
- Dexamethasone EP Impurity E
- Vamorolone (USAN/INN)
- 9,11-dehydro dexamethasone
- Agamree
- Agamree (TN)
- DEXAMETHASONE IMPURITY E
- VBP 15
- VBP-15 free alcohol
- vamorolona
- vamorolone
- vamorolonum