C9H16ClN3O2
233.69 g/mol
APIDanger
Lomustine
CAS13010-47-4EC235-859-2
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Lomustine is a nitrosourea compound used as an active pharmaceutical ingredient in the manufacture of anticancer medications. It has been identified as a carcinogen and developmental toxicant based on expert review and government labeling requirements.
Pharmaceutical raw material for anticancer drug manufacturingComponent in combination chemotherapy formulations for brain tumorsSecondary therapy agent for refractory or relapsed Hodgkin's disease
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 13010-47-4
Related Compounds
SimilarStructure SimilarSimilarity 0.77
1-NO-1(2CLET)-3(4-OH CYHEXYL)UREA
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SimilarStructure SimilarSimilarity 0.77
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Safety Reference
Danger
H228Flammable solid
H242Heating may cause a fire
H301Toxic if swallowed
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H371May cause damage to organs
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
InChIKey
GQYIWUVLTXOXAJ-UHFFFAOYSA-N
SMILES
C1CCC(CC1)NC(=O)N(CCCl)N=O
Synonyms (46)
- CCNU
- CINU
- Lomustina [INN-Spanish]
- Lomustine (JAN/USP/INN)
- Lomustine, European Pharmacopoeia (EP)
- Lomustine, United States Pharmacopeia (USP)
- Lomustinum [INN-Latin]
- Belustin
- Belustine
- CCNU; NSC 79037
- Cecenu
- CeeNU
- Citostal
- Gleostine
- Gleostine (TN)
- ICIG 1109
- LOMUSTINE [MART.]
- Lomeblastin
- Lomustina
- Lomustine (CeeNU)
- Lomustine (Standard)
- Lomustine - Bio-X trade mark
- Lomustine CRS
- Lomustinum
- Lucostin
- Lucostine
- Prava
- lomustine