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Home/Compounds/API/Buclizine dihydrochloride
C28H35Cl3N2
505.9 g/mol
API

Buclizine dihydrochloride

CAS129-74-8EC204-962-4
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Buclizine dihydrochloride is a hydrochloride salt form of buclizine, noted for its activity as a histamine antagonist, cholinergic antagonist, local anaesthetic, central nervous system depressant, and antiemetic. It is primarily utilized as an active pharmaceutical ingredient in pharmaceutical manufacturing and research.

pharmaceutical raw materialresearch compound for histamine antagonismresearch compound for antiemetic studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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ReferenceSame Category

Methyl [(5S,10R,11S,14S)-11-benzyl-5-tert-butyl-10-hydroxy-15,15-dimethyl-3,6,13-trioxo-8-{[4-(pyridin-2-yl)phenyl]methyl}-2-oxa-4,7,8,12-tetraazahexadecan-14-yl]carbamate (non-preferred name)

CAS1292296-09-3

pharmaceutical raw material

Referencesame scaffold

Meclizine hydrochloride

CAS31884-77-2

pharmaceutical raw material

Referencesame scaffold

Meclizine dihydrochloride

CAS1104-22-9

pharmaceutical raw material

Referencesame scaffold

Meclizine-d8 (hydrochloride)

CAS1432062-16-2

pharmaceutical raw material

Customs Tariff Classification

The international HS code for Buclizine dihydrochloride (CAS 129-74-8) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]piperazine;dihydrochloride

InChIKey

SDBHDSZKNVDKNU-UHFFFAOYSA-N

SMILES

CC(C)(C)C1=CC=C(C=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl

Synonyms (34)
  • Buclizine hydrochloride (USAN)
  • Aphilan
  • Aphilan R
  • Bucladin
  • Bucladin-S
  • Buclina
  • Buclizine HCl
  • Buclizine dihydrochloride
  • Buclizine hydrochloride
  • Buclodin
  • Equivert
  • Histabutyzine dihydrochloride
  • Histabutyzine hydrochloride
  • Longifene
  • Perlapine, >=98% (HPLC)
  • Postafeno
  • Softran
  • Vibazine
  • Vibazine (TN)
  • Vibazine hydrochloride
  • buclizine 2HCl

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