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Home/Compounds/Research Reagent/2'-OMe PAC Abeta-cyanoethyl phosphoramidite
C49H56N7O9P
918 g/mol
Research Reagent

2'-OMe PAC Abeta-cyanoethyl phosphoramidite

CAS128219-82-9
Category
Research Reagent
Compound Class
Amine
Primary Use
Research Compound

This compound is a phosphoramidite building block designed for oligonucleotide synthesis. It features a 2'-O-methyl modification and a phenoxyacetyl (PAC) protecting group on the adenine base, along with a 4,4'-dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl.

Oligonucleotide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.76

(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(hexadecyloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

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N6-Me-rA phosphoramidite

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research compound

SimilarStructure SimilarSimilarity 0.72

N-[9-[(2R,3R,4R,5R)-5-[(1S)-1-[bis(4-methoxyphenyl)-phenyl-methoxy]ethyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-3-methoxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide

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Identifiers
IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]-2-phenoxyacetamide

InChIKey

LHJMWCPLFQEOGK-JLZYTDEISA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N2C=NC3=C(N=CN=C32)NC(=O)COC4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

Synonyms (3)

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