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Home/Compounds/API/N-Desmethyl-6-O-methylerythromycin (9E)-Oxime
C37H68N2O13
748.9 g/mol
API

N-Desmethyl-6-O-methylerythromycin (9E)-Oxime

CAS127182-43-8
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material

N-Desmethyl-6-O-methylerythromycin (9E)-Oxime is a macrolide derivative used as a reference standard for quality control of clarithromycin. It is an impurity marker employed in the pharmaceutical industry to ensure the purity and identity of the active pharmaceutical ingredient.

Reference standard for clarithromycin impurity testingAnalytical standard in pharmaceutical quality controlResearch compound for impurity profiling studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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StrongStructure SimilarSimilarity 0.86

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Referencesame scaffold

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Referencesame scaffold

(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one

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Referencesame scaffold

PUBCHEM_71314812

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pharmaceutical research compound

Identifiers
IUPAC Name

(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-14-ethyl-12,13-dihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-6-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one

InChIKey

MPBKKWQXSHKTAP-UXZNNQEFSA-N

SMILES

CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/O)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)NC)O)(C)OC)C)C)O)(C)O

Synonyms (7)
  • 3''-N-Demethyl-6-O-methylerythromycin A (E)-9-oxime; Oxacyclotetradecane, erythromycin deriv.; Clarithromycin Imp. M (EP)
  • Clarithromycin EP impurity M