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Home/Compounds/Industrial Chemical/N,N-dimethylacetamide
C4H9NO
87.12 g/mol
Industrial ChemicalDanger

N,N-DIMETHYLACETAMIDE

CAS127-19-5EC204-826-4
Category
Industrial Chemical
Compound Class
Amide
Primary Use
Polar solvent in organic synthesis

N,N-Dimethylacetamide (DMAc) is a colorless, high-boiling, water-miscible liquid widely used as a polar solvent in organic synthesis. It is miscible with most other solvents but poorly soluble in aliphatic hydrocarbons.

Polar solvent in organic synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Restricted or banned substances

Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.

Relevant lists:EU REACH Restriction ListCalifornia Proposition 65

CAS 127-19-5

Related Compounds

ReferenceSame Category

Chloramine B

CAS127-52-6

antibacterial agent and disinfectant

ReferenceSame Category

Sodium m-nitrobenzenesulfonate

CAS127-68-4

antireduction agent in industrial processing

ReferenceSame Category

Titanocene dichloride

CAS1271-19-8

Ziegler-Natta polymerization catalyst

ReferenceSame Category

Ethylferrocene

CAS1273-89-8

organoiron compound for chemical synthesis

Referencestereoisomer of

N,N-Bis[(²H₃)methyl](²H₃)acetamide

CAS16727-10-9

pharmaceutical intermediate

Safety Reference

Toxic
Toxic
Harmful
Harmful
Health Hazard
Health Hazard
Danger
H312Harmful in contact with skin
H332Harmful if inhaled
H319Causes serious eye irritation
H360May damage fertility or the unborn child
H227
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H350May cause cancer
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H351Suspected of causing cancer
H320Causes eye irritation
H373May cause damage to organs through prolonged or repeated exposure
H303May be harmful if swallowed
H313May be harmful in contact with skin
H316Causes mild skin irritation
Regulatory Compliance3
  • EU REACH Restriction ListEURegulation
    RestrictedSource
  • EU REACH SVHCEURegulation
    Listed· listed since 2011-12-19Source
  • California Proposition 65USRegulation
    Listed· listed since 2019-09-13Source

Customs Tariff Classification

The international HS code for N,N-DIMETHYLACETAMIDE (CAS 127-19-5) is 2924.19.

HS code (international, 6-digit)

2924.19

EU CN code (8-digit)

2924 19 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

N,N-dimethylacetamide

InChIKey

FXHOOIRPVKKKFG-UHFFFAOYSA-N

SMILES

CC(=O)N(C)C

Synonyms (45)
  • 5Y9
  • U-5954
  • N, N-Dimethylacetamide, EP
  • Acetamide, N,N-dimethyl-
  • Acetdimethylamide
  • Acetic acid, dimethylamide
  • Acetyldimethylamine
  • DIMETHYLACETAMIDE [MART.]
  • DMAc
  • Dimethylacetamide
  • Dimethylacetone amide
  • Dimethylamid kyseliny octove
  • Dimethylamide acetate
  • Hallucinogen
  • N,N-DIMETHYLACETAMIDE
  • N,N-Dimethylacetamide, p.a.
  • N,N-Dimethylethanamide
  • N,N-dimethyacetamide
  • N,N-dimethylacetoamide
  • N,N-dimethylactamide
  • N-Acetyldimethylamine
  • N-N-Dimethylacetamide(DMAC)
  • dimeihyl acetamide
  • dimethyacetamide
  • dimethylactamide
  • dimethylacteamide
  • methane, dimethylcarbamoyl-
  • n-dimethylacetamide
  • trimethylformamide