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Home/Compounds/Pharmaceutical Intermediate/(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylic acid phenylmethyl ester
C30H24BrF2N3O2
576.4 g/mol
Pharmaceutical Intermediate

(S)-Benzyl 6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate

CAS1256388-49-4
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate specifically used in the manufacture of ledipasvir, an antiviral agent. It is a stereochemically defined molecule containing multiple aromatic rings, halogen atoms, and a spirocyclic amine structure.

Pharmaceutical intermediate for ledipasvir manufacturingLaboratory research reagentChemical building block for antiviral drug synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 1256388-49-4

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Related Compounds

SimilarStructure SimilarSimilarity 0.73

Tert-butyl (6S)-6-[5-(7-bromo-9,9-difluorofluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate

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pharmaceutical intermediate

ApplicationSame Use

Tert-butyl (1R,3S,4S)-3-(6-bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate

CAS1256387-74-2

pharmaceutical intermediate

ReferenceSame Category

N-[(1S)-1-[[(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl]carbonyl]-2-methylpropyl]carbamic acid methyl ester

CAS1256388-50-7

pharmaceutical intermediate

ReferenceSame Category

Ledipasvir Intermediate

CAS1256393-27-7

pharmaceutical intermediate

ReferenceSame Category

2-methyl-2-(4-vinylphenyl)propanoic acid

CAS1256584-72-1

pharmaceutical intermediate

ReferenceSame Category

2-(4-ethyl-3-iodophenyl)-2-methylpropanoic acid

CAS1256584-73-2

pharmaceutical intermediate

Identifiers
IUPAC Name

benzyl (6S)-6-[5-(7-bromo-9,9-difluorofluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate

InChIKey

HTUJXNNBCXWTGU-SANMLTNESA-N

SMILES

C1CC12C[C@H](N(C2)C(=O)OCC3=CC=CC=C3)C4=NC=C(N4)C5=CC6=C(C=C5)C7=C(C6(F)F)C=C(C=C7)Br

Synonyms (2)

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