Home/Compounds/Pharmaceutical Intermediate/N-[1-[(2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxopyrimidin-4-yl]benzamide
C35H32N4O4
572.7 g/mol
Pharmaceutical IntermediateWarning
Benzamide, N-(1,2-dihydro-1-(6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl)-2-oxo-4-pyrimidinyl)-, (2R-cis)-
CAS125515-31-3EC813-214-1
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a protected morpholino cytosine monomer intermediate specifically designed for oligonucleotide synthesis. Its structure features a trityl-protected morpholino ring and a benzamide-protected cytosine base, making it suitable for solid-phase synthesis of morpholino phosphorodiamidate oligomers.
Morpholino cytosine monomer intermediate for oligonucleotide manufacturingResearch reagent for nucleic acid chemistry
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 125515-31-3
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Referencesame scaffold
(6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate)
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Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
Identifiers
IUPAC Name
N-[1-[(2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChIKey
DMFVVKPXZHMPKX-XDFJSJKPSA-N
SMILES
C1[C@H](O[C@H](CN1C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6)CO
Synonyms (9)
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