C28H27N3O3
453.5 g/mol
APIWarning
Netarsudil
CAS1254032-66-0
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Netarsudil is a pharmaceutical active ingredient used in ophthalmic formulations. It is a rho kinase inhibitor intended for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
pharmaceutical raw material for ophthalmic formulationscompound used in manufacturing of glaucoma medications
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
ReferenceSame Category
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pharmaceutical raw material
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pharmaceutical raw material
ReferenceSame Category
(6S)-rotigotine hydrochloride
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pharmaceutical raw material
ReferenceSame Category
Ledipasvir
CAS1256388-51-8
pharmaceutical raw material
Safety Reference
Warning
H361Suspected of damaging fertility or the unborn child
Customs Tariff Classification
The international HS code for Netarsudil (CAS 1254032-66-0) is 2933.49.
HS code (international, 6-digit)
2933.49
EU CN code (8-digit)
2933 49 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
[4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate
InChIKey
OURRXQUGYQRVML-AREMUKBSSA-N
SMILES
CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)[C@@H](CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C
Synonyms (13)
- Netarsudil (USAN/INN)
- AR-11324 free base
- Netarsudil
- Netarsudil free base
- Rhokiinsa
- Rhopressa
- netarsudilum
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